Drag and Drop for file uploadFiles can’t be uploaded to libraries using Drag and Drop. When you try to do so, a not supported icon would be displayed
Features that require ActiveX componentsSome features in SharePoint require ActiveX components and will not work in Edge browser. These features include Open with Explorer, Open with Access, Open with Project. These options would be disabled on the list\library ribbon
Customize in InfoPath
Clicking Customize in InfoPath from the ribbon would say that you’ll need Internet explorer to use the feature.
Clicking Export to Excel from the ribbon will show a warning stating that you will require compatible application, however the functionality will work.
If the user has Lync\skype for business client installed on their machine and they hover over user name in SharePoint, the Lync Contact Card pops up showing information such as email, phone etc. This functionality depends on Active X and doesn’t work with Edge browser.